Oral medications for childhood constipation
Laxatives are always first line management of acute and chronic constipation in children. Follow our handy guide to understand the different types of laxative medications your child might be prescribed, how they work and where to find further information if required.
What are laxatives?
Laxatives are medications used to treat constipation. They are the recommended first line treatment for childhood constipation and they need to be prescribed by your child’s doctor.
There are various types of laxatives which can be summarised by the following diagram:
Laxatives need to be given correctly for them to work properly. The type of laxative your child is given will depend on their symptoms. The next section explains more about the different types of laxatives available for children.
It is important that you follow your doctor’s instructions about how much to give.
Types of laxatives
1. Osmotic laxatives
Osmotic laxatives act by delivering water to the large bowel, softening the poo and causing the gut muscle to squeeze.
(a).Macrogols e.g. Movicol, Cosmocol, Laxido, Strigol
- Macrogols are the first line treatment for constipation in children. This means that they are considered the best option available and should be considered for the initial treatment of childhood constipation.
- Macrogol laxatives work by ‘binding with’ water and delivering it to the large bowel. It is therefore essential to mix it with the correct amount of water or it will not work. This water cannot be absorbed through the bowel wall due to the size of the molecules. It stays in the bowel and combines with the poo to hydrate it, break up any hard lumps and soften it.
- Macrogols add water to the stool which bulks it up. This has a naturally stimulating effect -it moves the poo along the bowel.
- The macrogol water is drunk, goes through the gut and comes out the other end completely unchanged. On the way it does a good job of softening the poo and moving it along.
- For more details on how to give macrogol laxatives see How to use macrogol laxatives.
(b).Lactulose
- Lactulose is made up of complex sugar chains which the body can't break down, so it reaches the large bowel undigested. The body then tries to break it down by drawing water in, softening the stool.
- BUT it can only draw in very small amounts of water, so is only helpful in constipation which is very mild/caught very early.
- Lactulose is ineffective if the child is not drinking enough – it can't draw water into the bowel if there is not enough in the circulating bloodstream.
- As Lactulose is effectively liquid sugar, it is important to brush your child’s teeth after every dose. It may also increase wind, leading to an uncomfortable tummy.
- Lactulose can be useful in combination with other laxatives for children who will not take - but need - higher doses of macrogols.
2. Stimulant laxatives e.g.Senna, Sodium Picosulfate, Bisacodyl
Stimulant laxatives act on the nerves in the gut, causing the gut muscles to rhythmically squeeze and relax, pushing the poo through the gut.
- They are not recommended as first line treatment as they can cause tummy pain if they squeeze on poo which is stuck, and maybe hard. A stool softener should be taken first - ideally a macrogol, but otherwise Lactulose or Docusate Sodium.
- They have a timed mode of action taking between 6 and 12 hours to work. Look at the patient information leaflet to find out the expected timescale for each particular medicine.
- They are usually initially prescribed at night so any discomfort will not bother the child; the child will then be expected to poo in the morning. Once a child is used to taking stimulants some people choose to swap to taking them in the morning, if an evening poo is more convenient.
- Stimulants are available in different formats – tablets, liquids and capsules, dependent on dose and age.
3. Stool softeners (Docusate sodium)
- These decrease the surface tension of the poo which lets water into the poo, softening it and bulking it up. This bulking causes the gut to squeeze.
- They are not first line treatment due to the limited dose range, but can be useful for some children.
- They are available in a liquid, capsule or enema, dependent on dose and age.
How much laxative does my child need to take?
Constipation often fluctuates and therefore it can often be necessary to vary the amount of laxative you give your child. Laxatives have a dose range, so it may be useful to look at this so that you can discuss the right dose for your child with your doctor, should you feel the prescribed dose is not enough/too much.
Your doctor will work out the range of the dose that is right for your child. This range of doses will be shown on the medicine label. It may initially need to be increased to clear out any backlog of poo, then adjusted until your child passes a soft stool every day. Your doctor will advise you on this.
Information on all the medications discussed, including the dose ranges can be found here:
BNFC (British National Formulary for Children) | NICE
This table gives you a guide to the range of doses of the various laxatives that your doctor may prescribe.
It is important that you follow your doctor’s instructions about how much to give.
| Medicine | Age | Dose | Comments | ||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Macrogol (maintenance) | 1-11 months | ½-1 sachet | Paediatric sachets | ||||||||||||||||||||||||||||||||||||||
| Powder for solution | 1- 5years | 1-4 sachets | Paediatric sachets | ||||||||||||||||||||||||||||||||||||||
| 6-11 years | 2-4 sachets | Paediatric sachets | |||||||||||||||||||||||||||||||||||||||
| 12-18 years | 2 sachets 1-3 times per day for up to 2 weeks then 2 sachets 1-2 times per day | Adult sachets | |||||||||||||||||||||||||||||||||||||||
| Macrogol (disimpaction) Powder for solution | 1-11 months | Day 1: ½ -1 sachet Day 2: ½-1 sachet Day 3: ½-1 sachet Day 4: ½-1 sachet | Paediatric sachets Day 7 dose should be continued daily until disimpaction achieved. If not achieved after 2 weeks, add a stimulant | ||||||||||||||||||||||||||||||||||||||
| 1-5 years | Day 1:2 sachets Day 2: 4 sachets Day 3: 4 sachets Day 4: 6 sachets Day 5: 6 sachets Day 6: 8 sachets Day 7: 8 sachets | Paediatric sachets Day 7 dose should be continued daily until disimpaction achieved. If disimpaction not achieved after 2 weeks, add a stimulant. | |||||||||||||||||||||||||||||||||||||||
| 6-11 years | Day 1: 4 sachets Day 2: 6 sachets Day 3: 8 sachets Day 4: 10 sachets Day 5: 12 sachets Day 6: 12 sachets Day 7: 12 sachets | Paediatric sachets Day 7 dose should be continued daily until disimpaction achieved. If disimpaction not achieved after 2 weeks, add a stimulant. | |||||||||||||||||||||||||||||||||||||||
| Over 12 years | Day 1: 4 sachets Day 2: 6 sachets Day 3: 8 sachets Day 4: 8 sachets Day 5: 8 sachets Day 6: 8 sachets Day 7: 8 sachets | Adult sachets Day 7 dose should be continued daily until disimpaction achieved. If disimpaction not achieved after 2 weeks, add a stimulant. | |||||||||||||||||||||||||||||||||||||||
| Lactulose Syrup | 1 month-11 months | 2.5 mls | Twice daily | ||||||||||||||||||||||||||||||||||||||
| 1 year – 4 years | 2.5mls-10mls | Twice daily | |||||||||||||||||||||||||||||||||||||||
| 5 years – 18 years | 5- 20 mls | Twice daily | |||||||||||||||||||||||||||||||||||||||
| Senna | 1 month- 3 years | 3.75-15mg | Once daily | ||||||||||||||||||||||||||||||||||||||
| Syrup or tablets | 4 years – 17 years | 3.75-30mg | Once daily | ||||||||||||||||||||||||||||||||||||||
| Sodium Picosulfate | 1 month- 3 years | 2.5mg-10mg | Once daily | ||||||||||||||||||||||||||||||||||||||
| Syrup | 4 years- 17 years | 2.5mg – 20mg | Once daily | ||||||||||||||||||||||||||||||||||||||
| Bisacodyl tablets | 4 – 17 years | 5-20mg | Once daily | ||||||||||||||||||||||||||||||||||||||
| Docusate Sodium Liquid or capsules | 6 months – 23 months | 12.5mg | Three times a day (paediatric solution) | ||||||||||||||||||||||||||||||||||||||
| 2 years – 11 years | 12.5-25 mg | Three times a day (paediatric solution) | |||||||||||||||||||||||||||||||||||||||
| 12 years – 17 years | 100mg 3 times per day | (Up to 500mg daily) In divided doses | |||||||||||||||||||||||||||||||||||||||
You may see from the leaflet provided with the medication, that the product you have been given does not appear to be licensed for children your child’s age. However, lots of medicines are used ‘off-licence’ in childhood – the lack of licence does not mean they are in any way unsafe.
For further explanation and information please see Unlicensed medicines - Medicines For Children
How do I get my child to take their laxatives if they are reluctant?
Sometimes children do not like the taste or texture of medication, and they cannot always understand why they need to take it.
Here are our top tips for encouraging your child to take their medication:
- Take time to sit down with your child and explain what the medication is for and what it is supposed to do.
- Check with your doctor or pharmacist to see if there are any different flavour options for the medication your child has been prescribed e.g. Movicol is available in chocolate flavour!
- Check with your doctor or pharmacist to see if the medication is available in a different format (e.g. tablets instead of liquid) and whether they can be crushed or mixed with food.
- Try giving your child something cold to eat prior to taking the medication – this may change the taste of the medication.
- Try using a syringe or dropper to give liquid medication and place at the back of the tongue or side of the cheek.
- Try to give your child some choice over how they take the medication if you can (e.g. spoon or syringe, flavour).
- Practice pill swallowing once you feel your child is old enough. There are lots of good ideas in this resource: Helping your child to swallow tablets – new resources from Kidzmed – Medicines For Children
- Have a consistent routine with medication if possible. Plan for a quiet time with minimal stress and have distractions available for afterwards.
- Stay positive! Use lots of praise to build your child’s confidence.
- Learn through play – use teddies/dolls/ stories, to help your child understand what the medication is for and to work through any fears.
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Last Reviewed: October 2025
Next Review: October 2028
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